David J. Pinsky, M.D.

David J. Pinsky, MD, currently holds positions at Michigan as a Director of the University of Michigan’s Samuel and Jean Frankel Cardiovascular Center, an Executive Committee member of the Taubman Medical Research Institute, and the UM Director of the University of Michigan-Israel Partnership for Research and Education (MIP). He graduated with top honors from Sylvania Northview High School, the University of Toledo, and The Ohio State University College of Medicine. He studied internal medicine and heart failure at Mount Sinai in New York, then cardiology, nuclear cardiology, and vascular biology at Columbia University College of Physicians and Surgeons. He was recruited to the faculty at Columbia in 1992, where he served until his recruitment to the University of Michigan in 2003. At Michigan, he served a 20-year term as Chief of Cardiovascular Medicine and co-led the building of one of the most prominent Cardiovascular Centers in the nation.

Dr Pinsky

Dr. Pinsky is an inventor on over a dozen patents, co-founder of a company, an author of over 200 scientific papers and book chapters, and the leader of The Vascular Defense and Discovery Laboratory, focused on understanding how natural blood vessel defense mechanisms may be amplified to protect in conditions such as stroke, heart attack, or organ transplantation.

His current work focuses on a protective enzyme that lines blood vessels, amplifying a natural defense mechanism against unchecked inflammation and coagulation. His lab was the first to directly measure nitric oxide in the beating heart and to discover that very small amounts of carbon monoxide may actually protect blood vessels following flow interruption. His team also discovered a fundamental new mechanism by which white blood cells control their own destiny in the vicinity of a clotted vein or in a cholesterol-choked artery. Pinsky’s goal is to understand, amplify, and harness a blood vessel’s natural defenses in order to develop novel strategies for the treatment of vascular diseases. He has trained a generation of clinicians and researchers, many of whom have themselves gone on to prominent positions in academia and industry. Dr. Pinsky is an elected member of multiple honorary scientific societies, including the ASCI, AAP, ACCA, and the Association of University Cardiologists. He has served on and chaired numerous national peer-review and strategy panels for the American Heart Association, Department of Defense, and National Institutes of Health, and is a popular lecturer worldwide.

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